Zoracopan

Zoracopan is a selective complement factor D (CFD) inhibitor. When administered systemically (orally or intravenously), Zoracopan accumulates and is sustained-released in ocular tissues, primarily in the choroid-retinal pigment epithelium (C-RPE) and/or iridociliary body (I-CB) [1].

Product Specifications

CAS Number

[2243483-63-6]

UNSPSC

12352005

Target

Complement System

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/zoracopan.html

Purity

99.85

Solubility

DMSO : ≥ 100 mg/mL

Smiles

C[C@]12[C@](C2)([H])N([C@@H](C1)C(NC3=C(C=CC(Br)=N3)C)=O)C(CN4C5=C(C)C=C(C6=CN=C(C)N=C6)C=C5C(C(C)=O)=C4)=O

Molecular Formula

C31H31BrN6O3

Molecular Weight

615.52

References & Citations

[1]Ocular drug depot for complement-mediated disorders. WO2021183555A1 - Ocular drug depot for complement-mediated disorders - Google Patents.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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