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MMP-7-IN-2

MMP-7-IN-2 is a potent and selective inhibitor of MMP7 with an IC50 value of 16 nM. MMP-7-IN-2 can be used for the research of diseases such as cancer and fibrosis[1].

Product Specifications

CAS Number

[2848717-49-5]

UNSPSC

12352209

Target

MMP

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mmp-7-in-2.html

Purity

99.59

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=[S](N[C@H](C(O)=O)CCC(NCC(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N)=O)=O)=O)=O)=O)(C(C=C1)=CC(C(F)(F)F)=C1Cl)=O

Molecular Formula

C28H40ClF3N6O9S

Molecular Weight

729.17

References & Citations

[1]Hideaki Tabuse, et al. Discovery of Highly Potent and Selective Matrix Metalloproteinase-7 Inhibitors by Hybridizing the S1' Subsite Binder with Short Peptides. J Med Chem. 2022 Oct 13;65 (19) :13253-13263.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

MMP-1; MMP-12; MMP-13; MMP-14; MMP-2; MMP-3; MMP-7; MMP-8; MMP-9

Available Sizes

Curated Selection

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