Anti-Hu LAR APC
LAR is a receptore-linked transmembrane protein tyrosine phosphatase expressed on mesenchymal stem cells, that reside e.g. in bone marrow, blood, placenta, adipose tissue, or skin, as well as it is expressed on some carcinoma cell lines, including HeLa, MCF-7, or HT29. During the process of externalization, LAR is intracellularly proteolytically processed into two non-covalently associated subunits. This protein is involved in intercellular and cell-matrix interactions and its extracellular part resembles that of cell adhesion molecules (CAMs) . The extracellular part can be released from the surface, which may be used for regulation of LAR function.
Product Specifications
Certification
RUO
Immunogen
WERI-RB-1 retinoblastoma cells
Target Antigen
LAR
Clone
W7C6
Applications
FC (QC tested)
Concentration
0.1 mg/mL
Format
APC
Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
The mouse monoclonal antibody W7C6 recognizes an extracellular epitope of protein tyrosine phosphatase LAR, a marker of mesenchymal stem cells.
Applications Notes
Flow cytometry: Recommended dilution: 1-4 μg/ml.
Species
Non-human primates, Human
CAS Number
9007-83-4
Isotype
Mouse IgG1
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