PLAA Recombinant Protein
Product Specifications
CAS Number
9000-83-3
Gene Name
Phospholipase A2 activating protein
Gene Aliases
DOA1; DOA1 homolog; NDMSBA; phospholipase A-2-activating protein; PLA2P; PLAP.
Gene ID
9373
Accession Number
NP_001026859.1
Reactivity
Homo sapiens|Human
Target
Plays a role in protein ubiquitination, sorting and degradation through its association with VCP (PubMed:27753622) . Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling (By similarity) . May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes (PubMed:27753622) . Plays a role in cerebellar Purkinje cell development (By similarity) . Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF-alpha) - or lipopolysaccharide (LPS) -dependent manner, and hence prostaglandin E2 biosynthesis (PubMed:18291623, PubMed:28007986) .
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
14kDa
Protein Length
Recombinant
NCBI Gene Symbol
PLAA
Host or Source
E.coli
Protein Name
Phospholipase A-2-activating protein
Gene Name URL
PLAA
Nucleotide Accession Number
NM_001031689.2
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