IL10RB Recombinant Protein
Product Specifications
CAS Number
9000-83-3
Gene Name
Interleukin 10 receptor subunit beta
Gene Aliases
CDW210B; CRF2-4; CRFB4; cytokine receptor class-II CRF2-4; cytokine receptor class-II member 4; cytokine receptor family 2 member 4; cytokine receptor family II, member 4; D21S58; D21S66; IL-10 receptor subunit beta; IL-10R subunit 2; IL-10R subunit beta; IL-10R2; IL-10RB; interleukin 10 receptor, beta; interleukin-10 receptor subunit 2; interleukin-10 receptor subunit beta.
Gene ID
3588
Accession Number
NP_000619.3
Reactivity
Homo sapiens|Human
Target
Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.
Conjugation
Unconjugated
Type
Protein
Source
E.coli
Applications
Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
200 ug/mL (prior to lyoph)
Format
Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Reconstitution
2°C to 8°C|-80°C
Molecular Weight
18kDa
Protein Length
Recombinant
NCBI Gene Symbol
IL10RB
Host or Source
E.coli
Protein Name
Interleukin-10 receptor subunit beta
Gene Name URL
IL10RB
Nucleotide Accession Number
NM_000628.4
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