Cd68 Antibody - Biotin Conjugated
Product Specifications
CAS Number
9007-83-4
Gene Aliases
La, ma, Sca, gp11, Lamp4, gp110, Scard1
Gene ID
12514
Accession Number
NP_033983.1
Reactivity
Mouse
Immunogen
Purified Concanavalin A acceptor glycoprotein from P815 cell line.
Target
Mouse macrosialin is a heavily glycosylated transmembrane protein and murine homolog of human CD68, which is classified as a unique scavenger recept (ScR) family member, due to the presence of a lysosome associated membrane protein (LAMP) -like domain. CD68 is considered a pan macrophage marker, predominantly expressed on the intracellular lysosomes of tissue macrophages/monocytes, including Kupffer cells, microglia, histiocytes and osteoclasts, and is expressed to a lesser extent by dendritic cells and peripheral blood granulocytes. CD68 is expressed by many tumor types including some B cell lymphomas, blastic NK lymphomas, melanomas, granulocytic (myeloid) sarcomas, hairy cell leukemias, and renal, urinary and pancreatic tumors, and can be used in cancer studies to demonstrate the presence/localization of macrophages.
Clonality
Monoclonal
Clone
FA-11
Conjugation
Biotin
Type
Monoclonal Antibody
Applications
Flow cytometry|Immunohistochemistry-Frozen
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.1 mg/ml
Format
Liquid. Phosphate buffered saline
Reconstitution
-20°C
Notes
Formerly GWB-Q01481
Fragment
IgG2a
Specificity
CD68 (mouse macrosialin)
Protein Length
335
NCBI Gene Symbol
CD68
Host or Source
Rat
Protein Name
Macrosialin
Gene Name URL
Cd68
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