CD223 Rabbit Polyclonal Antibody

Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008], function:Involved in lymphocyte activation. Binds to HLA class-II antigens., similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain., similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains., tissue specificity:On cell surface of activated NK and T-lymphocytes.