LAMTOR3 Antibody - N-terminal
Product Specifications
CAS Number
9007-83-4
Gene Name
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Gene Aliases
Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3; MAP2K1IP1; MAPBP; MAPK scaffold protein 1; MAPKSP1; MEK binding partner 1; MEK-binding partner 1; mitogen-activated protein kinase kinase 1 interacting protein 1; Mitogen-activated protein kinase kinase 1-interacting protein 1; mitogen-activated protein kinase scaffold protein 1; MP1; PRO0633; ragulator complex protein LAMTOR3; Ragulator3.
Gene ID
8649
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_068805
Reactivity
Bovine|Chicken|Human|Mouse|Rat
Immunogen
LAMTOR3 antibody was raised against an 15 amino acid peptide near the center of human LAMTOR3. The immunogen is located within amino acids 40 - 90 of LAMTOR3.
Target
As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid. LAMTOR3 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
Predicted: 14 kDa Observed: 13 kDa
Fragment
IgG
NCBI Gene Symbol
LAMTOR3
Host or Source
Rabbit
Protein Name
Ragulator complex protein LAMTOR3|ragulator complex protein LAMTOR3 isoform 1 [Homo sapiens]
Gene Name URL
LAMTOR3
Nucleotide Accession Number
NM_001243736.1
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