LAMTOR2 Antibody - N-terminal
Product Specifications
CAS Number
9007-83-4
Gene Name
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
Gene Aliases
ENDAP; endosomal adaptor protein p14; HSPC003; late endosomal/lysosomal adaptor and MAPK and MTOR activator 2; late endosomal/lysosomal Mp1-interacting protein; MAPBP-interacting protein; MAPBPIP; MAPKSP1 adaptor protein; MAPKSP1AP; Mitogen-activated protein-binding protein-interacting protein; mitogen-activated protein-binding protein-interacting protein (MAPBPIP) ; p14; ragulator complex protein LAMTOR2; Ragulator2; roadblock domain containing 3; roadblock domain-containing protein 3; ROBLD3.
Gene ID
28956
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_054736
Reactivity
Bovine|Human|Mouse|Rat
Immunogen
LAMTOR2 antibody was raised against an 18 amino acid peptide near the center of human LAMTOR2. The immunogen is located within amino acids 40 - 90 of LAMTOR2.
Target
As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid. LAMTOR2 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
Predicted: 14 kDa Observed: 16 kDa
Fragment
IgG
NCBI Gene Symbol
LAMTOR2
Host or Source
Rabbit
Protein Name
Ragulator complex protein LAMTOR2|ragulator complex protein LAMTOR2 isoform 1 [Homo sapiens]
Gene Name URL
LAMTOR2
Nucleotide Accession Number
NM_001145264.1
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
