Duocarmycin A
Duocarmycin A is a potent DNA alkylating agent that selectively targets the N3 of adenine within AT-rich sequences, inducing apoptosis in cancer cells like HLC-2. This small molecule is widely used in oncology research to study DNA damage mechanisms and evaluate cytotoxic effects in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
118292-34-5
Field of Research
Cell Biology, Protein Biochemistry
Smiles
O=C1C=2[C@]34[C@] (C3) (CN (C (=O) C=5NC=6C (C5) =CC (OC) =C (OC) C6OC) C4=CC (=O) C2N[C@]1 (C (OC) =O) C) [H]
Molecular Formula
C26H25N3O8
Molecular Weight
507.49
Storage Conditions
-20°C
Notes
For research use only.
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