PARD3 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Par-3 family cell polarity regulator
Gene Aliases
ASIP; atypical PKC isotype-specific interacting protein; Atypical PKC isotype-specific-interacting protein; Baz; bazooka; CTCL tumor antigen se2-5; PAR3; par-3 family cell polarity regulator alpha; par-3 partitioning defective 3 homolog; PAR3alpha; PAR3-alpha; PARD-3; PARD3A; partitioning defective 3 homolog; PPP1R118; protein phosphatase 1, regulatory subunit 118; SE2-5L16; SE2-5LT1; SE2-5T2.
Gene ID
56288
Accession Number
NP_001171714
Reactivity
Human
Immunogen
Recombinant Human Partitioning defective 3 homolog protein (1068-1356AA)
Target
Adapter protein involved in asymmetrical cell division and cell polarization processes (PubMed:27925688, PubMed:10954424) . Seems to play a central role in the formation of epithelial tight junctions (PubMed:27925688) . Targets the phosphatase PTEN to cell junctions (By similarity) . Involved in Schwann cell peripheral myelination (By similarity) . Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly (By similarity) . The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (PubMed:10934474) . Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons (PubMed:19812038, PubMed:27925688) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Western blot
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
PARD3
Host or Source
Rabbit
Protein Name
Partitioning defective 3 homolog
Gene Name URL
PARD3
Nucleotide Accession Number
NM_001184785
Curated Selection
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