ACT1
ACT1 is a peptide that targets endogenous Cx43 by stabilizing its activity at gap junctions. ACT1 stabilizes gap junction intercellular communication in breast cancer cells. ACT1 enhances the activity of Tamoxifen (HY-13757A) and Lapatinib (HY-50898) in breast cancer. ACT1 can be used for breast cancer research[1].
Product Specifications
UNSPSC
12352209
Target
Gap Junction Protein
Related Pathways
Cytoskeleton
Field of Research
Cancer
Smiles
O=C(N[C@@H](CCC(N)=O)C(N1[C@@H](CCC1)C(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(N[C@@H](CC4=CC=CC=C4)C(N5[C@@H](CCC5)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N6[C@@H](CCC6)C(N[C@@H](CC7=CNC8=CC=CC=C78)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N9[C@@H](CCC9)C(N[C@@H](CCCNC(N)=N)C(N%10[C@@H](CCC%10)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@@H](C)CC)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N
Molecular Formula
C150H238N48O34
Molecular Weight
3257.80
References & Citations
[1]Grek CL, et al. Targeting connexin 43 with α-connexin carboxyl-terminal (ACT1) peptide enhances the activity of the targeted inhibitors, tamoxifen and lapatinib, in breast cancer: clinical implication for ACT1. BMC Cancer. 2015 Apr 3;15:296.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P11197/
Scientific Category
Peptides
Clinical Information
No Development Reported
CAS Number
[895547-36-1]
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Monoclonal TCR alpha Antibody (F1) [FITC]](https://cdn.genprice.uk/genprice/genprice4.png)
MBS6505121-01 0.1 mL
USP12, CT (Ubiquitin Carboxyl-terminal Hydrolase 12, Ubiquitin Thiolesterase 12, Ubiquitin-specific Processing Protease 12, Deubiquitinating Enzyme 12, Ubiquitin Hydrolyzing Enzyme 1, UBH1, USP12L1) (MaxLight 750)
Ask
View Details MBS6505121-02 5x 0.1 mL
USP12, CT (Ubiquitin Carboxyl-terminal Hydrolase 12, Ubiquitin Thiolesterase 12, Ubiquitin-specific Processing Protease 12, Deubiquitinating Enzyme 12, Ubiquitin Hydrolyzing Enzyme 1, UBH1, USP12L1) (MaxLight 750)
Ask
View Details MBS1306644 Inquire
Recombinant Chicken Prospero homeobox protein 1 (PROX1), partial
Ask
View Details