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MAP2K1 Antibody (Phospho-Ser221)

Product Specifications

CAS Number

9007-83-4

Gene Name

Mitogen-activated protein kinase kinase 1

Gene Aliases

MEL, CFC3, MEK1, MKK1, MAPKK1, PRKMK1

Gene ID

5604

Swiss Prot

Q02750

Accession Number

NP_002746.1

Reactivity

Human, Mouse, Rat

Immunogen

A phospho-Serpecific peptide corresponding-Thro residues-Serurrounding-Ser221 of human MAP2K1

Target

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

WB, IHC, IF

Purification

Affinity purified against immunogen

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Reconstitution

Store at -20C. Avoid repeated freeze/thaw cycles.

Molecular Weight

45 kDa

Fragment

IgG

NCBI Gene Symbol

MAP2K1

Host or Source

Rabbit

Protein Name

Dual specificity mitogen-activated protein kinase kinase 1

Gene Name URL

MAP2K1

Nucleotide Accession Number

NM_002755.3

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