Protein kinase inhibitor 5
Product Specifications
UNSPSC Description
Protein kinase inhibitor 5 is a potent TRK-A inhibitor with an IC50 value of 1.8 nM. Protein kinase inhibitor 5 inhibits cell viability[1].
Target Antigen
Trk Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling;Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protein-kinase-inhibitor-5.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=C2N=C(N3[C@@H](C4=CC(F)=CC=C4F)CCC3)C=CN2N=C1)C5=CC=C(CN6CCN(C)CC6)C=C5
Molecular Weight
531.60
References & Citations
[1]Dawei Zhang, et al. Substituted pyrazolopyrimidines useful as kinases inhibitors. WO2019029629A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153745/Protein-kinase-inhibitor-5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153745/
Clinical Information
No Development Reported
CAS Number
2278204-94-5
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