Anti-GSK-3 Alpha Polyclonal Antibody
Product Specifications
Gene Name
Glycogen synthase kinase 3 alpha
Gene Aliases
Glycogen synthase kinase-3 alpha; GSK-3 alpha; serine/threonine-protein kinase GSK3A.
Gene ID
2931
Swiss Prot
P49840
Reactivity
Human|Mouse|Rat
Immunogen
A synthetic peptide corresponding to N-terminus of human GSK3-alpha protein. This sequence is identical among human, mouse and rat.
Target
Glycogen Synthase Kinase-3 has two isoforms, GSK-3alpha and GSK3beta. GSK3 is a serine/threonine kinase that affects glycogen metabolism by phosphorylating and down-regulating the activity of muscle glycogen synthase as well as the regulation in Wnt signal pathway. GSK-3 alpha reduces the substRates beta-catenin and tau to imply an important role in Wnt signaling and tauopathies such as Alzheimer's disease..
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Flow cytometry|Immunohistochemistry|Immunoprecipitation|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
100ug/200ul
Format
Liquid. This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
Reconstitution
The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
Molecular Weight
52
Fragment
Rabbit IgG
Specificity
GSK3A
NCBI Gene Symbol
GSK3A
Host or Source
Rabbit
Gene Name URL
GSK3A
CAS Number
9007-83-4
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