What is the catalog number for MORF4L1 Antibody?

The catalog number for MORF4L1 Antibody is OAAF02720-100UG.

What sizes are available for MORF4L1 Antibody?

MORF4L1 Antibody is available in the following size(s): 100 µg.

Is MORF4L1 Antibody in stock?

MORF4L1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

MORF4L1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Mortality factor 4 like 1

Gene Aliases

Eaf3; Esa1p-associated factor 3 homolog; FWP006; HsT17725; MEAF3; MORF-related gene 15 protein; MORF-related gene on chromosome 15; MORFRG15; mortality factor 4-like protein 1; MRG15; protein MSL3-1; S863-6; transcription factor-like protein MRG15.

Gene ID

10933

Swiss Prot

Q9UBU8

Accession Number

NP_001252532.1

Reactivity

Human|Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human MORF4L1.

Target

Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC) . Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol