SSX2 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Aliases

SSX, HD21, CT5.2, CT5.2A, HOM-MEL-40

Gene ID

6757

Swiss Prot

Q16385-2

Accession Number

NP_783629

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human SSX2

Target

SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t (X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

Partner Proteins

KRT40; SSX2IP; RAB3IP; SYCE1; ZMIZ2; MAGEC2; AKAP9; ZBED1; TAX1BP1; BLZF1; SUZ12; EED; SMARCA5; TLE1; SMARCA2; HDAC2; HDAC1; EZH2; ATF2; RNF2

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

TFGRLQGISPKIMPKKPAEEG NDSEEVPEASGPQNDGKELCPPGKPTTS

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol