DMBP
DMBP is a VPS41 inhibitor. DMBP induces methuosis and inhibits autophagy in cancer cells. DMBP inhibits the fusion of late endosomes and autophagosomes with lysosomes. DMBP effectively inhibits metastasis in a mouse metastatic melanoma model. DMBP can be used for the study of melanoma[1].
Product Specifications
CAS Number
[133156-42-0]
UNSPSC
12352005
Target
Autophagy
Related Pathways
Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Purity
99.7800
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OC)C1=C(CCC2=CC=CC=C2)C=C(O)C(C/C=C(C)\C)=C1O
Molecular Formula
C21H24O4
Molecular Weight
340.41
References & Citations
[1]Liu Y, et al. Targeting VPS41 induces methuosis and inhibits autophagy in cancer cells. Cell Chem Biol. 2023 Feb 16;30 (2) :130-143.e5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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