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DMBP

DMBP is a VPS41 inhibitor. DMBP induces methuosis and inhibits autophagy in cancer cells. DMBP inhibits the fusion of late endosomes and autophagosomes with lysosomes. DMBP effectively inhibits metastasis in a mouse metastatic melanoma model. DMBP can be used for the study of melanoma[1].

Product Specifications

CAS Number

133156-42-0

UNSPSC

12352005

Target

Autophagy

Related Pathways

Autophagy

Applications

COVID-19-immunoregulation

Field of Research

Cancer

Purity

99.7800

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(OC)C1=C(CCC2=CC=CC=C2)C=C(O)C(C/C=C(C)\C)=C1O

Molecular Formula

C21H24O4

Molecular Weight

340.41

References & Citations

[1]Liu Y, et al. Targeting VPS41 induces methuosis and inhibits autophagy in cancer cells. Cell Chem Biol. 2023 Feb 16;30 (2) :130-143.e5.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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