Wdr5 Antibody - C-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

WD repeat domain 5

Gene Aliases

Big, Big-, Big-3, AA408785, AA960360, 2410008O07Rik

Gene ID

140858

Swiss Prot

P61965

Accession Number

NP_543124

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

Target

Wdr5 contributes to histone modification. It may position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. It may regulate osteoblasts differentiation.

Partner Proteins

L3mbtl2; Phf20; Rbbp5; Csrp2bp; Mbip; Kat2a; Rnf2; Pou5f1; Runx1; Ctcf; Nfe2; Kmt2d; Kdm2b; Sall4; Tfcp2l1; Esrrb; Nr0b1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

NFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTEN

Applications

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol