NFIL3 Antibody - N-terminal region

Product Specifications

CAS Number

9007-83-4

Gene Name

Nuclear factor, interleukin 3 regulated

Gene Aliases

E4BP4, IL3BP1, NFIL3A, NF-IL3A

Gene ID

4783

Swiss Prot

Q14211

Accession Number

NP_005375

Reactivity

Human, Cow, Dog, Pig, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NFIL3

Target

NFIL3 is a basic leucine zipper (bZIP) transcription factor that represses or activates transcription in non-osteoblastic cells. NFIL3 play a role in attenuation of PTH target gene transcription in osteoblasts. NFIL3 repression domain interacts specifically with the TBP binding repressor protein Dr1.Glucocorticoid-mediated upregulation of the bZIP transcriptional repressor gene, NFIL3, is dependent on [Ca2+]i levels, and correlates with Glucocorticoid-evoked apoptosis of Glucocorticoid-sensitive CEM-C7-14 cells. NFIL3 is involved in a distinct growth factor-regulated signaling pathway that is responsible for the survival of early B-cell progenitors, and whose alteration by E2A-HLF leads to childhood B lineage leukemia.

Partner Proteins

AMOTL2; TRAF2; MAFF; BATF; NFIL3; MAFG; DDIT3; CBX8; SUMO2; UBC; CREB3; DR1

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

MQLRKMQTVKKEQASLDASSNVDKMMVLNSALTEVSEDSTTGEDVLLSEG

Applications

WB, IHC

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 86%; Dog: 86%; Human: 100%; Pig: 79%; Sheep: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

51kDa

Protein Length

462

NCBI Gene Symbol

NFIL3

Host or Source

Rabbit

Protein Name

Nuclear factor interleukin-3-regulated protein

Gene Name URL

NFIL3

Nucleotide Accession Number

NM_005384

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

ENZ-ABS134A-0100 100 µg

RNA polymerase II monoclonal antibody (H14)

Ask

View Details

MF-0148290-01 100 mg

Sp-8-Cl-cAMPS

Ask

View Details

MF-0148290-02 25 mg

Sp-8-Cl-cAMPS

Ask

View Details

MF-0148290-03 50 mg

Sp-8-Cl-cAMPS

Ask

View Details

MBS7087855 Inquire

Recombinant Human Lipoma HMGIC fusion partner-like 2 protein (LHFPL2), partial

Ask

View Details

abx381732 96 Tests

Human NADH Ubiquinone Oxidoreductase Complex Assembly Factor 4 (NDUFAF4) ELISA Kit

Ask

View Details