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HMGB1 antibody - N-terminal region (ARP38109_P050)

Product Specifications

CAS Number

9007-83-4

Gene Name

High mobility group box 1

Gene Aliases

HMG1, HMG3, HMG-1, SBP-1

Gene ID

3146

Swiss Prot

P09429

Accession Number

NP_002119

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human HMGB1

Target

HMGB1 belongs to the HMGB family. It contains 2 HMG box DNA-binding domains. The protein binds preferentially single-stranded DNA and unwinds double stranded DNA. The oxidized HMGB1 may accumulate even in cells under oxidative stress.

Partner Proteins

AGTRAP; HUWE1; UBC; ASB2; ASB1; ZNF24; MAPK1; HMGA1; ITGA4; FN1; HNF1A; SSRP1; SMARCE1; PSEN1; XPC; XPA; RAD23B; CDK2; TFAP4; TERF2IP; TERF2; HHV8GK18_gp81; SUMO2; FCP1; DNM2; HSPA8; HMGB2; PDIA3; Ccdc15; POU5F1; H3F3A; CREBBP; CDK1; TBP; LRIF1; RASSF4; N

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

GKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKT

Applications

WB

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

25kDa

Protein Length

215

NCBI Gene Symbol

HMGB1

Host or Source

Rabbit

Protein Name

High mobility group protein B1

Gene Name URL

HMGB1

Nucleotide Accession Number

NM_002128

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