CHRNA7 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Cholinergic receptor, nicotinic, alpha 7 (neuronal)

Gene Aliases

NACHRA7, CHRNA7-2

Gene ID

1139

Swiss Prot

P36544

Accession Number

NP_000737

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CHRNA7

Target

The protein encoded by CHRNA7 displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. This gene is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia.

Partner Proteins

ATXN1; ADCY6; PIK3R1; APP; FYN

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

VPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRF

Applications

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1.0 mg/ml

Homology

Cow: 100%; Dog: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

56kDa

Protein Length

502

NCBI Gene Symbol

CHRNA7

Host or Source

Rabbit

Protein Name

Neuronal acetylcholine receptor subunit alpha-7

Gene Name URL

CHRNA7

Nucleotide Accession Number

NM_000746

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

33R-8195 100 ug

KRT15 Blocking Peptide

Ask

View Details

HY-116312 1 Each

8-pCPT-2′-O-Me-cAMP

Ask

View Details

343791-01 100 µL

HNK-1ST discontinued

Ask

View Details

343791-02 200 µL

HNK-1ST discontinued

Ask

View Details

PVT15678 2 µg

pECMV-Sirt3-m-FLAG Plasmid

Ask

View Details

V9358-100UG 100 µg

NOC4L Antibody

Ask

View Details