NOC4L Antibody
Treg activation is critical for maintaining self-tolerance, but the translational control of this process is still poorly understood. Zhu et al. report a conserved ribosome biogenesis factor, Noc4L, that regulates mRNAs related to Treg and Tconv activation but does not affect global protein translation. Noc4L regulates translation of mRNAs related to Treg activation. Noc4L plays critical roles in activation of Tregs and Tconvs. Noc4L-mediated ribosome biogenesis is critical in controlling the activation of Tregs and maintaining immune tolerance. [Zhu et al., 2019, Cell Reports 27, 1205 1220.]
Product Specifications
UniProt
Q9BVI4
Host
Mouse
Immunogen
Recombinant full-length human NOC4L protein was used as the immunogen for the NOC4L antibody.
Clonality
Monoclonal
Isotype
IgG1
Applications
FACS, IF
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the NOC4L antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This NOC4L antibody is available for research use only.
CAS Number
9007-83-4
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Fibroblast Growth Factor Receptor 1 (FGFR1, Basic fibroblast growth factor receptor 1, BFGFR, bFGF-R, CD331, CEK, c-fgr, FGFBR, FGFR-1, FLG, FLJ99988, FLT2, Fms-like tyrosine kinase 2, H2, H3, H4, H5, HBGFR, KAL2, N-SAM, OGD) (BSA & Azide Free)
