Apelin-36 (human)
Product Specifications
CAS Number
252642-12-9
Target
Apelin receptor|||HIV Protease
Related Pathways
Microbiology/Virology|||Proteases/Proteasome|||GPCR/G Protein
Bioactivity
Endogenous APJ receptor agonist (EC50 = 20 nM) that is secreted by adipocytes. Binds with high affinity to human APJ receptors expressed in HEK 293 cells (pIC50= 8.61) . Involved in regulation of cardiovascular function, fluid homeostasis and feeding. Blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ.
Molecular Formula
C184H297N69O43S
Molecular Weight
4195.87
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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