Cimidahurinine
Product Specifications
CAS Number
142542-89-0
Target
Bcl-2 Family|||ROS
Related Pathways
Immunology/Inflammation|||Apoptosis
Bioactivity
Cimidahurinine can attenuate Doxorubicin (DOX) -induced cardiotoxicity in a dose-dependent manner with EC50 values of 45.79 uM; it protects against cardiotoxicity by decreasing reactive oxygen species (ROS) accumulation and downregulating apoptosis-related Bax/Bcl-2 proteins.
Smiles
OCCc1ccc(O)c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1
Molecular Formula
C14H20O8
Molecular Weight
316.3
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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