Flavoglaucin
Product Specifications
CAS Number
523-73-9
Target
Nrf2, NF-κB, NOS, IL Receptor, Phosphatase, COX, Autophagy, Prostaglandin Receptor, TNF
Related Pathways
Metabolism, Apoptosis, GPCR/G Protein, Immunology/Inflammation, Neuroscience, Autophagy, NF-κB
Bioactivity
Flavoglaucin exhibits significant inhibitory effects on PTP1B, the IC50 value of 13.4, micrometer; it also shows good binding affinity for human opioid or cannabinoid receptors. Flavoglaucin appears to be an antitumor promoter, it also has anti-inflammatory effects, it shows inhibitory effects on inflammatory mediators via the induction of heme oxygenase-1 in lipopolysaccharide-stimulated RAW264.7 macrophages. Flavoglaucin exhibits a significant radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) with theIC (50) value of 11.3 microM.
Smiles
CCCCCCCc1c(O)cc(CC=C(C)C)c(O)c1C=O
Molecular Formula
C19H28O3
Molecular Weight
304.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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