Iptacopan hydrochloride
Product Specifications
CAS Number
1646321-63-2
Target
Complement System
Related Pathways
Immunology/Inflammation
Purity
0.9989
Bioactivity
Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. Iptacopan hydrochloride shows direct, reversible, and high-affinity binding to human factor B with a KD of 7.9 nM.
Smiles
Cl.CCO[C@H]1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)[C@@H](C1)c1ccc(cc1)C(O)=O
Molecular Formula
C25H31ClN2O4
Molecular Weight
458.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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