Human TRAIL R3 protein, His Tag (MALS verified)

Tumor necrosis factor receptor superfamily member 10C (TNFRSF10C) is also known as Decoy receptor 1 (DcR1), TNF-related apoptosis-inducing ligand receptor 3 (TRAIL receptor 3 or TRAIL-R3), CD263. TNFRSF10C is a decoy receptor for TRAIL (tumor necrosis factor-related apoptosis-inducing ligand), a member of the tumor necrosis factor (TNF) ligand family. This receptor is not capable of inducing apoptosis (lacks a cytoplasmic death domain), and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis.

Product Specifications

Background

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 24 kDa. The protein migrates as 43-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

O14798

Expression Region

Ala 26 - Pro 235

Host

HEK293

Target

TRAIL R3

Conjugation

Unconjugated

Tag

C-10xHis

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Bioactivity

Immobilized Human TRAIL R3 protein, His Tag (Cat. No. TR3-H52H3) at 5 μg/mL (100 μL/well) can bind Human TRAIL, Mouse IgG2a Fc Tag (Cat. No. TRL-H5259) with a linear range of 0.008-0.5 μg/mL (QC tested).