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CID44216842

Product Specifications

CAS Number

1222513-26-9

Target

Ras|||CDK

Related Pathways

GPCR/G Protein|||MAPK|||Cell Cycle/Checkpoint

Purity

0.9966

Bioactivity

CID44216842 (KUC103479N-02) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 ?M in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 ?M in GDP binding assay, respectively. Use as a molecular probe.

Smiles

COc1cccc(c1)C1=NN(C(C1)c1ccc(Br)cc1)c1ccc(cc1)S(N)(=O)=O

Molecular Formula

C22H20BrN3O3S

Molecular Weight

486.38

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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