PROTAC BRAF-V600E degrader-1

2417296-84-3

Raf|||PROTACs

MAPK|||PROTAC

0.9943

PROTAC BRAF-V600E degrader-1 (Compound 23) selectively induces degradation of BRAF-V600E but not wildtype BRAF.

FC1=C(N2C=3C(C(=C2)C=4C=NC=NC4)=NC(N(C)C5CCN(C(CCOCCOCCOCCNC6=C7C(C(=O)N(C7=O)C8C(=O)NC(=O)CC8)=CC=C6)=O)CC5)=CC3)C(F)=CC=C1NS(CCC)(=O)=O

C48H54F2N10O10S

1001.07

Cool pack

-20°C