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N- (Phenylacetyl-d5) glycine

N- (Phenylacetyl-d5) glycine is the deuterium labeled Phenylacetylglycine. Phenylacetylglycine is a gut microbial metabolite that can activate β2AR. Phenylacetylglycine protects against cardiac injury caused by ischemia/reperfusion[1][2].

Product Specifications

CAS Number

1189920-31-7

Product Name Alternative

2- (2-Phenylacetamido) acetic acid-d5

UNSPSC

12352005

Target

Adrenergic Receptor; Apoptosis; Endogenous Metabolite

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cardiovascular Disease

Purity

99.0

Solubility

DMF : ≥ 25mg/mL|DMSO : ≥ 10mg/mL|Ethanol : ≥ 1mg/mL

Smiles

OC(CNC(CC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])=O)=O

Molecular Formula

C10H6D5NO3

Molecular Weight

198.23

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Xu X, et al. The gut microbial metabolite phenylacetylglycine protects against cardiac injury caused by ischemia/reperfusion through activating β2AR. Arch Biochem Biophys. 2021 Jan 15;697:108720.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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