PI-1840
Product Specifications
CAS Number
1401223-22-0
Target
Autophagy, Apoptosis, PARP, Caspase, NF-κB, Bcl-2 Family, Proteasome
Related Pathways
NF-κB, Proteases/Proteasome, Autophagy, DNA Damage/DNA Repair, Apoptosis, Ubiquitination, Chromatin/Epigenetic
Purity
>99.99%
Bioactivity
PI-1840 (IC50 = 27 nM) is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L) .
Smiles
CCCc1ccc(OCC(=O)N(Cc2nc(no2)-c2cccnc2)C(C)C)cc1
Molecular Formula
C22H26N4O3
Molecular Weight
394.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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