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AUZ 454

Product Specifications

CAS Number

853299-07-7

Target

CDK

Related Pathways

Cell Cycle/Checkpoint

Purity

0.9959

Bioactivity

AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd values of 50 nM for CDK2 (WT), 18.6 nM for CDK2 (C118L), 15.4 nM for CDK2 (A144C), and 9.7 nM for CDK2 (C118L/A144C) .

Smiles

CN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4ccnc(N)n4)cc3)cc2C(F)(F)F)CC1

Molecular Formula

C24H26F3N7O2

Molecular Weight

501.5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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