WAY-600
Product Specifications
CAS Number
1062159-35-6
Target
Src|||mTOR|||VEGFR|||PI3K
Related Pathways
Angiogenesis|||Tyrosine Kinase/Adaptors|||PI3K/Akt/mTOR signaling
Purity
0.9988
Bioactivity
WAY-600 is a potent, ATP-competitive, and selective inhibitor of mTOR with an IC50 of 9 nM; it blocks mTORC1/P-S6K (T389) and mTORC2/P-AKT (S473) but not P-AKT (T308), and is selective for mTOR over PI3K? (>100-fold) and PI3K? (>500-fold) .
Smiles
C(N1CCC(CC1)n1ncc2c(nc(nc12)-c1ccc2[nH]ccc2c1)N1CCOCC1)c1cccnc1
Molecular Formula
C28H30N8O
Molecular Weight
494.59
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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