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m-PEG-azide (MW 2000)

Product Specifications

UNSPSC Description

m-PEG-azide (MW 2000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG-azide (MW 2000) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Target Antigen

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/m-peg-azide-mw-2000.html

Solubility

10 mM in DMSO

Smiles

COCCOCCN=[N+]=[N-].[n].[MW 2000]

Molecular Weight

2000(Average)

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-140682/m-PEG-azide-MW-2000-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-140682/

Clinical Information

No Development Reported

Curated Selection

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