Vatalanib dihydrochloride

Product Specifications

CAS Number

212141-51-0

Target

PDGFR, VEGFR, Apoptosis

Related Pathways

Angiogenesis, Tyrosine Kinase/Adaptors, Apoptosis

Purity

>99.99%

Bioactivity

Vatalanib dihydrochloride (PTK787 dihydrochloride) (IC50=37 nM) is an inhibitor of VEGFR2/KDR. It exhibits less effective against VEGFR1/Flt-1 and 18-fold against VEGFR3/Flt-4.

Smiles

Cl.Cl.Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1

Molecular Formula

C20H15ClN4·2HCl

Molecular Weight

419.73

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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