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CCT373566

Product Specifications

CAS Number

2378853-66-6

Target

Others, Molecular Glues, Bcl-2 Family

Related Pathways

Others, Apoptosis, PROTAC

Bioactivity

CCT373566 is a potent, orally active degrader of the transcriptional repressor BCL6 (IC50: 2.2 nM) . CCT373566 exhibits significant anti-proliferative effects in vitro and reduces tumour growth in vivo.

Smiles

O=C1C2=C(C=3C(N1C)=CC=C(NC4=NC(=NC=C4Cl)N5C[C@@H](C)C[C@@H](O)C5)C3)N[C@H](C(F)(F)CO2)C6CC6

Molecular Formula

C26H29ClF2N6O3

Molecular Weight

547

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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