NRX-103095
Product Specifications
CAS Number
2763260-38-2
Target
Wnt/beta-catenin
Related Pathways
Stem Cells, Cytoskeletal Signaling
Purity
0.9995
Bioactivity
NRX-103095 is a potent enhancer of the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP and enhances the affinity of pSer33/Ser37 β-catenin for β-TrCP with an EC50 of 163 nM.
Smiles
S(C1=C(C(NC2=CC(C(N(C)C)=O)=CC=C2)=O)C(=O)NC(C(F)(F)F)=C1)C3=C(Cl)C=CC=C3Cl
Molecular Formula
C22H16Cl2F3N3O3S
Molecular Weight
530.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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