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LRRK2-IN-4

Product Specifications

CAS Number

2641054-59-1

Target

Others, LRRK2

Related Pathways

Others, Autophagy

Bioactivity

LRRK2-IN-4 is a potent, selective, orally active leucine-rich repeat kinase 2 (LRRK2) inhibitor that crosses the blood-brain barrier with an IC50 value of 2.6 nM. LRRK2-IN-3 has shown investigational potential in [Parkinson's disease].

Smiles

FC1(F)[C@H](C1)N2C(C)=C(NC3=NC4=C(C=N3)C=C(Cl)C(=C4)C5CCN(CC5)[C@]6(C)[C@H](O)COC6)C=N2

Molecular Formula

C25H29ClF2N6O2

Molecular Weight

518.99

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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