Acid Phosphatase (ACP1) (NM_004300) Human Recombinant Protein
Product Specifications
Background
The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2008]
Synonyms
HAAP; LMW-PTP; LMWPTP
Gene ID
52
UniProt
P24666, Q59EH3
Accession Number mRNA
NM_004300
Chromosomal Location
2p25.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Adherens junction, Riboflavin metabolism
Field of Research
Adherens junction, Riboflavin metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Phosphatase, Transmembrane
Molecular Weight
17.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ACP1
Species
Human
Protein ID
NP_004291
Overview
Recombinant protein of human acid phosphatase 1, soluble (ACP1), transcript variant 3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/52
Uniprot URL
https://www.uniprot.org/uniprot/P24666
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004300
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004291
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