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Acid Phosphatase (ACP1) (NM_004300) Human Recombinant Protein

Product Specifications

Background

The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2008]

Overview

Recombinant protein of human acid phosphatase 1, soluble (ACP1), transcript variant 3

Synonyms

HAAP; LMW-PTP; LMWPTP

Gene ID

52

UniProt

P24666, Q59EH3

Accession Number mRNA

NM_004300

Chromosomal Location

2p25.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Adherens junction, Riboflavin metabolism

Field of Research

Adherens junction, Riboflavin metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Phosphatase, Transmembrane

Molecular Weight

17.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ACP1

Species

Human

Protein ID

NP_004291

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/52

Uniprot URL

https://www.uniprot.org/uniprot/P24666

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004300

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004291

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