Ulecaciclib
Product Specifications
CAS Number
2075750-05-7
Target
Others, CDK
Related Pathways
Others, Cell Cycle/Checkpoint
Bioactivity
Ulecaciclib is an orally active, blood-brain barrier-transparent, cell cycle protein-dependent kinase (CDK) inhibitor that exhibits favorable pharmacokinetic profiles, with ki of 0.62 μM (CDK2/Cyclin A), 3 nM (CDK6/Cyclin D3), 0.2 nM (CDK4/Cyclin D1) and 0.63 μM (CDK7/Cyclin H) for CDKs. D1) and 0.63 μM (CDK7/Cyclin H) .
Smiles
CC1=C(SC(NC2CCCC2)=N1)C3=NC(NC4=CC=C(CN5CCN(CC)CC5)C=N4)=NC=C3F
Molecular Formula
C25H33FN8S
Molecular Weight
496.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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