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RET-IN-9

Product Specifications

CAS Number

2649418-11-9

Target

Others, c-RET

Related Pathways

Tyrosine Kinase/Adaptors, Apoptosis, Others

Bioactivity

RET-IN-9 is a potent inhibitor of RET, a single-channel transmembrane receptor tyrosine kinase involved in kidney and enteric nervous system development, as well as in maintaining homeostasis in the nervous, endocrine, hematopoietic, and male reproductive systems. RET-IN-9 is potentially useful in studying RET-related diseases, including non-small cell lung cancer and medullary thyroid cancer.

Smiles

C(#N)C1=C2C(=CC(NCC)=CN2N=C1)C=3C=NC(=CN3)N4CC5N(CC=6C=CC(OC)=NC6)C(C4)C5

Molecular Formula

C26H27N9O

Molecular Weight

481.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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