MRAS (NM_012219) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Synonyms
M-RAs; NS11; R-RAS3; RRAS3
Gene ID
22808
UniProt
O14807, Q6FGP0, Q8WVM9
Accession Number mRNA
NM_012219
Chromosomal Location
3q22.3
Expression System
E. coli
Tag
N-His
Related Pathways
MAPK signaling pathway, Regulation of actin cytoskeleton, Tight junction
Field of Research
MAPK signaling pathway, Regulation of actin cytoskeleton, Tight junction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Druggable Genome
Molecular Weight
23.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MRAS
Species
Human
Protein ID
NP_036351
Overview
Purified recombinant protein of Human muscle RAS oncogene homolog (MRAS), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/22808
Uniprot URL
https://www.uniprot.org/uniprot/O14807
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_012219
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_036351
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