Peficitinib hydrochloride
Product Specifications
CAS Number
1353219-06-3
Target
Others, JAK
Related Pathways
Tyrosine Kinase/Adaptors, Others, Chromatin/Epigenetic, JAK/STAT signaling, Stem Cells, Angiogenesis
Bioactivity
Peficitinib hydrochloride, also known as ASP015K, is an orally active JAK inhibitor compound. It exhibits inhibitory activity against JAK1, JAK2, JAK3, and Tyk2, with IC 50 values of 3.9, 5.0, 0.7, and 4.8 nM, respectively.
Smiles
Cl.[H][C@]12CC3C[C@]([H])(CC(O)(C3)C1)[C@H]2Nc1c(cnc2[nH]ccc12)C(N)=O
Molecular Formula
C18H23ClN4O2
Molecular Weight
362.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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