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VO-OHPic

Product Specifications

CAS Number

675848-25-6

Target

Others, Autophagy, PTEN, Apoptosis

Related Pathways

Autophagy, Apoptosis, Others, PI3K/Akt/mTOR signaling

Bioactivity

VO-OHPic is a reversible, noncompetitive, and selective inhibitor of PTEN with an IC50 of 46 nM, effectively attenuating apoptosis, adverse cardiac remodeling, and the presence of pro-inflammatory M1 macrophages in models of doxorubicin-induced cardiomyopathy. Additionally, VO-OHPic inhibits autophagy [1] [2] [3].

Smiles

[O-][V]=O.OC(=O)c1ncccc1O.OC(=O)c1ncccc1O

Molecular Formula

C12H10N2O8V

Molecular Weight

361.16

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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