Semagacestat
Product Specifications
Target
Gamma-secretase|||Beta Amyloid
Related Pathways
Proteases/Proteasome|||Stem Cells|||Neuroscience
Purity
0.999
Bioactivity
Semagacestat (LY450139) (LY450139) is a ?-secretase blocker for A?42/A?40/A?38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM) .
Smiles
CC(C)[C@H](O)C(=O)N[C@@H](C)C(=O)N[C@H]1c2ccccc2CCN(C)C1=O
Molecular Formula
C19H27N3O4
Molecular Weight
361.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/D23F76F2-2F3E-4F67-9D50-E17A2D4884DD/T6125
CAS Number
425386-60-3
Available Sizes
Curated Selection
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