Recombinant Rat Ceacam1/BGP-1 protein (His Tag)

Product Specifications

Background

Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner (By similarity) . Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an activator during angiogenesis. Its coinhibitory receptor function is phosphorylation-and PTPN6-dependent, which in turn, suppress signal transduction of associated receptors by dephosphorylation of their downstream effectors.Plays a role in immune response, of T-cells, natural killer (NK) and neutrophils.

Abbreviation

Ceacam1; BGP-1

Synonyms

Antigen CD66; BGP 1; Bgp1; Biliary glycoprotein 1; Biliary glycoprotein D; CD66a; CEACAM1; Carcinoembryonic antigen-related cell adhesion molecule 1; MHV-R; MHVR1; Murine hepatitis virus receptor; meconium antigen 100

UniProt

P16573

Accession Number

P16573

Expression System

E.coli

Tag

N-His & C-His

Sequence

Gln35-Ala425

Applications

Immunogen

Endotoxin

< 10 EU/mg of the protein as determined by the LAL method.

Purity

> 90% as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.