VEGFR-2/DHFR-IN-2
Product Specifications
Target
Others, VEGFR, Antifungal, DHFR, Antibacterial
Related Pathways
Metabolism, Microbiology/Virology, Tyrosine Kinase/Adaptors, Angiogenesis, Cell Cycle/Checkpoint, Others, DNA Damage/DNA Repair
Bioactivity
VEGFR-2/DHFR-IN-2 (compound 5b) is a dual inhibitor targeting VEGFR-2 and DHFR, with respective IC50 values of 0.623 μM and 9.085 μM. It demonstrates potent cytotoxicity against C26, HepG2, and MCF7 cancer cell lines, with IC50 values ranging from 3.59 μM to 8.38 μM. VEGFR-2/DHFR-IN-2 holds promise for cancer research [1].
Molecular Formula
C21H21NO4
Molecular Weight
351.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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