Recombinant Mouse CD112/Nectin-2 Protein (His Tag)
Product Specifications
Background
Nectin-2 (CD112) is a member of the nectin family, which contains two Ig-like C2-type domains and one Ig-like V-type domain in the extracellular region. Nectins are type I transmembrane glycoproteins that are calcium-independent immunoglobulin (Ig) -like cell adhesion molecules (CAMs) . Nectin2 is widely expressed in human tissues including brain, spinal cord, spleen, kidney, heart and liver. It can form trans-heterodimers with PVRL3/nectin-3 and interacts with CD226. Mutations of alleles of the murine CD112 gene can result in conditions such as morphologically aberrant spermatozoa. It may function in allergic reactions, and accordingly may used as a novel target for anti-allergic therapy.
Abbreviation
CD112; Nectin-2
Synonyms
CD112; Herpes virus entry mediator B; Herpesvirus entry mediator B; HveB; Murine herpes virus entry protein B; Poliovirus receptor homolog; Poliovirus receptor-related protein 2; Pvrl2; mHveB; nectin2
Accession Number
P32507
Expression System
HEK293 Cells
Tag
C-His
Sequence
Gln32-Gly351
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/5gkrtp
Product MSDS
https://789.bio/eb/TSiTu1
Calculated Molecular Weight
35.6 kDa
Observed Molecular Weight
40-45 kDa
Species
Mouse
Available Sizes
Curated Selection
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