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Xanthine oxidase-IN-5

Product Specifications

CAS Number

2276711-87-4

Target

Others|||Xanthine Oxidase

Related Pathways

Metabolism|||Others

Bioactivity

Xanthine oxidase-IN-5, a powerful and orally active inhibitor of xanthine oxidase (XO), exhibits an IC50 value of 0.70 ?M. It possesses favorable drug-like characteristics, with ligand efficiency (LE) and lipophilic ligand efficiency (LLE) values of 0.33 and 3.41, respectively. Moreover, Xanthine oxidase-IN-5 showcases significant hypouricemic effects in a hyperuricemic rat model [1].

Smiles

O(CC1=CN(CC2=CC(OC)=CC=C2)N=N1)C3=C(C=O)C=C(F)C=C3

Molecular Formula

C18H16FN3O3

Molecular Weight

341.34

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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